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Navigation / Overview |
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Alois Alzheimer |
Medical Aspects |
Alzheimer Patients |
Case Study: Iris Murdoch |
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LONI |
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Medical Aspects |
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Alzheimer’s Disease, progressive brain
disorder that causes a gradual and irreversible decline in memory,
language skills, perception of time and space, and, eventually, the
ability to care for oneself. First described by German psychiatrist
Alois Alzheimer in 1906, Alzheimer’s disease was initially thought
to be a rare condition affecting only young people, and was referred
to as presenile dementia. Today late-onset Alzheimer’s disease is
recognized as the most common cause of the loss of mental function
in those aged 65 and over. Alzheimer’s in people in their 30s, 40s,
and 50s, called early-onset Alzheimer’s disease, occurs much less
frequently, accounting for less than 10 percent of the estimated 4
million Alzheimer’s cases in the United States.
Source:
Encarta |
Cloze exercise
(htm with explanations) on Alzheimer's Disease: [doc]
[pdf]
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TRACKING MEMORY'S DECLINE
Powerful
imaging techniques can detect changes, over time, in parts of the human
brain linked to Alzheimer's and related disorders.
Target Areas:
Frontal, Parietal, Temporal Areas
Important
centers for a variety of memory functions: verbal, visual, new memory,
working memory, etc. PET scanners can detect levels of glucose
metabolism in areas of the brain that are important for memory. |

WSJ |
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1. The
hippocampus - Deep inside the brain, the hippocampus is important for
learning and short-term memory. Believed to be the site where short-term
memory is converted to long-term for storage elsewhere in the brain.
Repeated MRI scans over time can reveal volume loss.
2. Entorhinal
cortex - Scientists believe that Alzheimer's dementia begins here. It's
an area with direct connections to the hippocampus. Degeneration can
interfere with the ability of the hippocampus to get information from
the rest of the brain. This region begins to atrophy or shrink, probably
10 to 20 years before any visible signs or symptoms appear.
Sources:
National Institute on Aging; New York University School of Medicine
(PET, MRI images) |
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Famous Alzheimer's Patients |
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List of famous Alzheimer
patients: Ronald Reagan, Rita Hayworth, Iris Murdoch, Winston
Churchill, Ralph Waldo Emerson, Henry Ford, Maurice Ravel .....
(read more)
Did you know that
Alzheimer’s disease can affect even the rich and famous?
Former President of USA, Mr
Ronald Reagan, has Alzheimer’s disease.
Many myths and
misconceptions prevail about Alzheimer’s disease. It is not only the
common man but some physicians too who lack a proper understanding of
this disease.
http://w3.whosea.org/alzheimer/myths.htm |
Why We Dig Charlton Heston
Charlton Heston, simply put, is the greatest leading man in film
history. The charisma, dignity, grace and strength he conveyed on the
silver screen define what it is to be a leading man. Heston has screen
presence in biblical proportions, and its appropriate that his prime
came about while Hollywood had an obsession with making epics -- the
gravitas he embued in his characters made him a perfect fit in Tinsel
Town's Golden Era. There has never been anyone else quite like him
before or since and there may never be.
Charlton
Heston Online Shrine
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Case Study: Iris Murdoch (Alzheimer's in fiction) |
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Writer Iris Murdoch has Alzheimer's disease LONDON
(AP) February 4, 1997
When the acclaimed
novelist and philosopher Dame Iris Murdoch became vague and forgetful,
she attributed it to writer's block. Doctors have determined the cause
is Alzheimer's disease.
A woman who once was able to assemble an entire novel in
her head can no longer remember the titles of her books, said John
Bayley, the literary critic and professor of English who married Murdoch
in 1956.
"Iris has Alzheimer's. There is no doubt about it,"
Bayley told the Daily Telegraph.
"Being a very intelligent woman, she has managed to cover
it up for some time -- there is a facade of social graces. But as soon
as you scratch the surface, she is profoundly amnesic."
The diagnosis was verified by Dr. John Hodges, a
neurologist who has visited 77-year-old Murdoch twice at her home in
Oxford, the newspaper said.
Bayley said Murdoch first became forgetful about four
years ago, losing her way on a trip to London to visit friends.
Six months ago, the novelist likened her recent inability
to write to being in "a hard, dark place," from which was trying to
escape.
"Now, I'm afraid I am waiting in vain," the Daily
Telegraph quoted her as saying. "Perhaps I had better find some other
kind of job."
Bayley, 71, told newspaper: "One of the tragedies is that
she has forgotten so much about her own life and cannot tell you the
names of any of the books she has written. She has a striking language
problem."
Born in Dublin and educated at Oxford and Cambridge
universities, Murdoch has written 26 novels -- the first, Under the Net,
in 1954. Described as psychological detective stories, they depict
complicated sexual relationships, usually between professionals, and her
plots often contain a touch of the comic, the macabre, or the weird.
Her 1961 novel, A Severed Head, was dramatized by the
writer J.B. Priestley; The Sea, The Sea, a searing story about a theatre
director and his childhood love, won the Booker Prize in 1978.
Murdoch, who has also taught and written about
philosophy, was made a Dame of the British Empire in 1987. |
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Professor John Bayley announces Alzheimer's Society -
Iris Murdoch Research Fellowship 20 Nov 2000
Professor John
Bayley, husband of the late Dame Iris Murdoch, will today announce the
setting up of an Alzheimer's Society - Iris Murdoch Research Fellowship
to promote new research into communication by and with people with
dementia. Opening the 1st International Quality Research in Dementia
Conference in London, Professor Bayley will say:
"It is fitting
and appropriate that Iris Murdoch's name should be leant to research
that will further our understanding of the communication difficulties
faced by people with dementia and those close to them. I hope
investigations in this under-researched field will lead to tangible
improvements in the way we communicate with those suffering from this
devastating disease." People with dementia face increasing difficulties
in understanding what is said or what is going on around them as their
disease progresses. They gradually lose their speech, endlessly repeat
the same words or cry out from time to time. What is sometimes seen as
challenging behaviour exhibited by people with dementia is often an
attempt by the person to communicate. Very little is known about the way
in which dementia affects the language centres of the brain and the
Alzheimer's Society - Iris Murdoch Research Fellowship will focus on
this area.
Applications
for the Alzheimer's Society - Iris Murdoch Research Fellowship will be
invited in due course. It is expected that the Fellowship will be for
three years with funding up to Ł150,000.
The Society's
director of research, Dr Richard Harvey, commented:
"People with
dementia should be encouraged to communicate in whatever way seems most
appropriate in order to help them preserve their own sense of identity
and improve their quality of life. Topics for the fellowship might
include the psycho linguistics of dementia or the use of non-verbal
communication with people with dementia. This research fellowship will
therefore play an invaluable role in furthering our understanding in
this field and in helping us to better communicate with people with
dementia in the future." Over 500 scientists and carers attending the
four-day Quality Research in Dementia conference will hear papers
presenting new and recent research on the causes of dementia, genetics,
current and future treatments and quality of care. |
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Iris (2001/I)
(IMDb)
Directed
by: Richard Eyre
Writing
credits: John Bayley (books) Richard Eyre (screenplay) ... (more)
Tagline:
Her greatest talent was for life
Plot
Outline: True story of the lifelong romance between novelist Iris
Murdoch and her husband John Bayley, from their student days through her
battle with Alzheimer's disease. (more) (view trailer)
User
Comments: Over-rated bio-pic of famous writer (more)
User
Rating: 7.2/10 (2,549 votes)
Cast :
| Judi Dench-Iris Murdoch |
Jim Broadbent-John Bayley |
Kate Winslet-Young Iris |
Hugh Bonneville-Young John
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BBC Obituary,
9 February 1999 |
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